Is it possible to setup triple screens with the side monitors different from the center? Center = 2560x1080 34" ultra wide 21x9 L&R = 1920x1080 27" 16x9
Take a look at Documents folder for triplescreensettings.xml there you'll find options for each monitor physical widths and pixels I don't have any experience modifying those settings but I believe it is possible to set. And please, don't forget to backup your original config just in case.
It should be possible but, check out Custom Resolution Utility for another way to get them working. There are video tutorials showing how to configure triples, even of different sizes and refresh rates. I created a custom resolution that works in quite a few titles (that don't support triples) so I can run games without having to use Nvidia Surround mode. If you run into issues where the combined monitors are not centered, Resize Racoon works great to solve that.