After updating Windows 10 to the just released Fall Creators Update, NVIDIA Anti-Antialising preset settings in AMS Config do not work anymore and have no effect, leaving the game without AA. Trying to force AA settings for AMS.exe in the NVIDIA Control Panel has no effect as well. I'm using the latest NVIDIA drivers available as of today. A reinstall of the drivers does not fix it. It's probably a Windows 10 or NVIDIA problem but it would be nice if it could be investigated, in case there is a simple fix. In the meantime, if you want AA on NVIDIA, do not update to the Fall Creators Update yet. Also reported on the NVIDIA forum, in the Fall Creator Update thread (post #45): https://forums.geforce.com/default/...-update-feedback-thread-released-10-17-17-/1/ EDIT: AA works fine if launching the game in windowed mode, including borderless. It does not work for fullscreen mode only. EDIT2: there is a workaround involving Nvidia Profile Inspector. See post #14 for details.